Iorio Group

Apps, Tools and Computable Manuscripts

Structural Bias Benchmark

Benchmark of state-of-the-art computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data.

CELLector

Patient-genomics-guided selection of cancer in vitro models allowing in-silico drug/target prescriptions.

CeSta

Integrative ensemble predictor of cetuximab sensitivity in colorectal cancer PDXs from their basal multi-omic characterisation.

coRe

Identification of core fitness genes from joint analyses of multiple genome-wide CRISPR-Cas9 screens.

CRISPRcleanR

Pre-processing of CRISPR-KO screening data and correction of gene independent responses to CRISPR-Cas9 targeting.

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HT-29 Benchmark

Benchmarking pipeline and R package for evaluating CRISPR screens data quality.

MinTEs

Reduced gene templates for supervised analysis of scale-limited CRISPR-Cas9 fitness screens.